Many products are infused with CBD oil including tinctures, edible products, capsules and topical creams. Before delving into the study linking CBD to potential liver damage, it’s important to understand what CBD oil is. CBD isolate is just CBD, while full-spectrum is CBD with other cannabinoids, terpenes, and nutrients found in the hemp plant. Full-spectrum is actually the most popular option and may be the best one to choose for your dog with liver disease as it also contains additional nutrients.
What’S The Best Way To Administer Cbd To My Dog?
- Beverages, in general, are always going to be a popular product.
- Further, our hemp plants grow in the best locations – on sunny fields close to the Alps, with rubidium-rich soil that gives the hemp the full spectrum of CBD compounds – which is then harvested and processed by hand.
- The possibility of including CBD in a range of beverages allows one of the most popular products to hit the beverage scene since bottled water.
Researchers from the University of Arkansas for Medical Sciences did a study looking at possible liver damage in mice linked to CBD. The research, published in the Molecules Journal, showed that people using CBD might be at higher risk for liver toxicity. It’s extracted from the hemp of a cannabis plant and it doesn’t make you feel high like marijuana, because it contains little if any THC.
” In the Epidiolex human trials, the patients who were at the greatest risk for liver impairment were the ones taking extremely high doses of Epidiolex (20 mg/kg/day). At this potency, an 150 lb patient would be taking upwards of 1400 mg CBD per day . The average person we surveyed takes between 25 and 100 mg CBD per day. We also must not forget that this CBD gummies liver impairment occurred primarily in patients who had pre-existing liver problems or in patients taking other anti-seizure medications in conjunction with Epidiolex. Although animal models are often used to predict possible impacts on human health, various problems can arise when researchers make predictions about human health based on the results of such studies.
Cbd, Dosage And The Mouse Study
This includes chronic alcoholism, but is not limited to the same. With this kind of damage, the normally soft and rubbery liver becomes hard and lumpy. Interestingly, the researchers found a direct correlation to the use of cannabis and lower risk of fatty liver disease. Occasional users had about a 15% lower risk of developing the condition. However, it is also a growing health concern for those who have poor diets and are sedentary.
It is a condition that already affects one in three US citizens. FLD is also spreading in countries where obesity is reaching epidemic proportions. Journalists found that liver damage is a potential side effect named on the packaging of Epidiolex.
Although animal models may suggest a potential issue, human trials will be the only sure way to determine if CBD really does cause liver damage. The healthy cells become damaged over time because of disease or poor lifestyle habits.
The packaging states that patients’ liver enzymes need to be monitored while they’re on the medication and in the drug’s clinical trials, anywhere from 5% to 20% of patients showed elevated enzyme levels. Researchers used all guidelines and safety recommendations for the Epidiolex drug to conduct their study. Mice that were administered high levels of CDB showed liver damage symptoms within 24 hours and 75% of those animals died or were close to death within a few days. While there are a lot of promising findings relating to the use of CBD, it’s not all good news.